I study genomics and allergenic properties of house dust mites, and the many fascinating ways they interact with the environment, humans, and other organisms. At Purdue, we will conduct a global survey of wild house dust mites, create a probabilistic model of mite invasion to human houses from wild habitats following climate change, and predict their allergenic propensities based on conservatism/variability of known IgE epitopes. We will also explore the possibility of creating a universal vaccine treating mite-induced allergic disorders using a murine model.